About MPS I & MPS II
Mucopolysaccharidosis type I (MPS I) and mucopolysaccharidosis type II (MPS II) are part of a subgroup of lysosomal storage disorders (LSDs) called the mucopolysaccharidoses (MPSs). They are inherited, progressive, life-threatening diseases that share many clinical features and can be difficult to distinguish clinically. They are, however, biochemically -BREAK- distinct entities.1read more
Testing & Diagnosis
Diagnosis with MPS I/MPS II is usually prompt in individuals with severe phenotypes as they develop obvious and rapidly progressing signs and symptoms. However, individuals with attenuated forms of MPS I/MPS II may experience significant diagnostic delays.3,4
MPS I & II Case Studies
Read case studies that highlight important aspects of MPS I and MPS II diagnosis.
Testing and Diagnosis
Diagnosis with MPS I/MPS II is usually prompt in individuals with severe phenotypes as they develop obvious and rapidly progressing signs and symptoms.
Management of the Condition
Managing MPS I & MPS II
MPS I and MPS II are managed using a combination of disease-specific therapies, conventional symptomatic treatments, and surgical interventions.